Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer

Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer

Summary: Esophageal squamous-cell carcinoma (ESCC) is commonly treated with radiotherapy; however, radioresistance hinders its clinical effectiveness, and the underlying mechanism remains elusive. Here, we develop patient-derived xenografts (PDXs) from 19 patients with ESCC to investigate the mechan...

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Bibliographic Details
Main Authors: Xinyu Yang, Xinjie Chen, Shaosen Zhang, Wenyi Fan, Ce Zhong, Tianyuan Liu, Guoyu Cheng, Liang Zhu, Qingyi Liu, Yiyi Xi, Wen Tan, Dongxin Lin, Chen Wu
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Reports
Subjects:
CP: Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723012822

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http://www.sciencedirect.com/science/article/pii/S2211124723012822

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