Insulin Resistance Does Not Impair Mechanical Overload-Stimulated Glucose Uptake, but Does Alter the Metabolic Fate of Glucose in Mouse Muscle

Insulin Resistance Does Not Impair Mechanical Overload-Stimulated Glucose Uptake, but Does Alter the Metabolic Fate of Glucose in Mouse Muscle

Skeletal muscle glucose uptake and glucose metabolism are impaired in insulin resistance. Mechanical overload stimulates glucose uptake into insulin-resistant muscle; yet the mechanisms underlying this beneficial effect remain poorly understood. This study examined whether a differential partitionin...

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Bibliographic Details
Main Authors: Luke A. Weyrauch, Shawna L. McMillin, Carol A. Witczak
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
exercise
glucose transporter
glycogen
glycolysis
hexosamine pathway
lactate
Online Access:https://www.mdpi.com/1422-0067/21/13/4715

Internet

https://www.mdpi.com/1422-0067/21/13/4715

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