Tissue content of metalloproteinase-9 and collagen in the colon with and without fecal stream after intervention with infliximab in rats subjected to Hartmann’s surgery

Tissue content of metalloproteinase-9 and collagen in the colon with and without fecal stream after intervention with infliximab in rats subjected to Hartmann’s surgery

ABSTRACT Purpose Quantify the tissue content of metalloproteinase-9 (MMP-9) and collagen in colic mucosa with and without intestinal transit after infliximab administration in rats subjected to Hartmann’s surgery. Methods Twenty-two rats underwent colon diversion by Hartmann’s surgery. Animals wer...

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Bibliographic Details
Main Authors: Antonio José Tiburcio Alves Junior, José Aires Pereira, Mariane Grandi de Ávila, Fernanda Aparecida Domingues, Daniela Tiemi Sato, Carlos Augusto Real Martinez
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021-05-01
Series:Acta Cirúrgica Brasileira
Subjects:
Colitis
Volatile Fatty Acids
Tumor Necrosis Factor-alpha
Collagen
Matrix Metalloproteinase 9
Rats
Free Oxygen Radicals
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502021000400201&tlng=en

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