Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF

Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF

Abstract Background Several common retinal diseases that cause blindness are characterised by pathological neovascularisation accompanied by inflammation and neurodegeneration, including retinopathy of prematurity (ROP), diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinal...

Full description

Bibliographic Details
Main Authors: Ruiyan Fan, Lin Su, Hui Zhang, Yilin Jiang, Zihao Yu, Xiaomin Zhang, Xiaorong Li
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Nanobiotechnology
Subjects:
Mesenchymal stem cells
Small extracellular vesicles
Pigment epithelium-derived factor
Oxygen-induced retinopathy mouse model
Online Access:https://doi.org/10.1186/s12951-023-02066-z

Internet

https://doi.org/10.1186/s12951-023-02066-z

Similar Items