Chlorogenic Acid Decreases Glutamate Release from Rat Cortical Nerve Terminals by P/Q-Type Ca<sup>2+</sup> Channel Suppression: A Possible Neuroprotective Mechanism

Chlorogenic Acid Decreases Glutamate Release from Rat Cortical Nerve Terminals by P/Q-Type Ca<sup>2+</sup> Channel Suppression: A Possible Neuroprotective Mechanism

The glutamatergic neurotransmitter system has received substantial attention in research on the pathophysiology and treatment of neurological disorders. The study investigated the effect of the polyphenolic compound chlorogenic acid (CGA) on glutamate release in rat cerebrocortical nerve terminals (...

Full description

Bibliographic Details
Main Authors: Yi-Chieh Hung, Yi-Hsiu Kuo, Pei-Wen Hsieh, Ting-Yang Hsieh, Jinn-Rung Kuo, Su-Jane Wang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
chlorogenic acid
glutamate release
P/Q-type Ca<sup>2+</sup> channel
CaMKII
neuroprotection
cerebral cortex
Online Access:https://www.mdpi.com/1422-0067/22/21/11447

Internet

https://www.mdpi.com/1422-0067/22/21/11447

Similar Items