Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia

Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia

Abstract The genomes of most protozoa encode families of variant surface antigens. In some parasitic microorganisms, it has been demonstrated that mutually exclusive changes in the expression of these antigens allow parasites to evade the host’s immune response. It is widely assumed that antigenic v...

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Bibliographic Details
Main Authors: Albano H. Tenaglia, Lucas A. Luján, Diego N. Ríos, Cecilia R. Molina, Victor Midlej, Paula A. Iribarren, María A. Berazategui, Alessandro Torri, Alicia Saura, Damián O. Peralta, Macarena Rodríguez-Walker, Elmer A. Fernández, Juan P. Petiti, Marianela C. Serradell, Pablo R. Gargantini, Tim Sparwasser, Vanina E. Alvarez, Wanderley de Souza, Hugo D. Luján
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38317-8

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https://doi.org/10.1038/s41467-023-38317-8

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