CAR-T Cells Targeting Immune Checkpoint Pathway Players

CAR (Chimeric antigen receptor)-T cell therapy has become a very promising type of immunotherapy against hematological cancers. This report is focused on CAR-T cells targeting immune checkpoint proteins expressed on tumor cells. The CD70, CD47, CD80, CD86, B7H3, B7H4, PDL-1, TIGIT CAR-T cells and ot...

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Bibliographic Details
Main Author: Vita Golubovskaya
Format: Article
Language:English
Published: IMR Press 2022-04-01
Series:Frontiers in Bioscience-Landmark
Subjects:
Online Access:https://www.imrpress.com/journal/FBL/27/4/10.31083/j.fbl2704121