Endothelial Heme Dynamics Drive Cancer Cell Metabolism by Shaping the Tumor Microenvironment

Endothelial Heme Dynamics Drive Cancer Cell Metabolism by Shaping the Tumor Microenvironment

The crosstalk among cancer cells (CCs) and stromal cells within the tumor microenvironment (TME) has a prominent role in cancer progression. The significance of endothelial cells (ECs) in this scenario relies on multiple vascular functions. By forming new blood vessels, ECs support tumor growth. In...

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Bibliographic Details
Main Authors: Sara Petrillo, Francesco De Giorgio, Joanna Kopecka, Tullio Genova, Veronica Fiorito, Anna Lucia Allocco, Francesca Bertino, Deborah Chiabrando, Federico Mussano, Fiorella Altruda, Luca Munaron, Chiara Riganti, Emanuela Tolosano
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biomedicines
Subjects:
cancer cell metabolism
tumor microenvironment
endothelial cell metabolism
tumor endothelial cells
heme metabolism
FLVCR1a
Online Access:https://www.mdpi.com/2227-9059/9/11/1557

Internet

https://www.mdpi.com/2227-9059/9/11/1557

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