Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way

Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way

The transplantation of pluripotent stem-cell-derived neurons constitutes a promising avenue for the treatment of several brain diseases. However, their potential for the repair of the cerebral cortex remains unclear, given its complexity and neuronal diversity. Here, we show that human visual cortic...

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Bibliographic Details
Main Authors: Ira Espuny-Camacho, Kimmo A. Michelsen, Daniele Linaro, Angéline Bilheu, Sandra Acosta-Verdugo, Adèle Herpoel, Michele Giugliano, Afsaneh Gaillard, Pierre Vanderhaeghen
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Cell Reports
Subjects:
brain repair
cerebral cortex
pluripotent stem cells
brain transplantation
neural wiring
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718306727

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http://www.sciencedirect.com/science/article/pii/S2211124718306727

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