CircRNA itchy E3 ubiquitin protein ligase improves mitochondrial dysfunction in sepsis-induced acute kidney injury by targeting microRNA-214-3p/ATP-binding cassette A1 axis

CircRNA itchy E3 ubiquitin protein ligase improves mitochondrial dysfunction in sepsis-induced acute kidney injury by targeting microRNA-214-3p/ATP-binding cassette A1 axis

AbstractBackground Circular RNAs (circRNAs) are promising biomarkers and therapeutic targets for acute kidney injury (AKI). In this study, we investigated the mechanism by which circRNA itchy E3 ubiquitin protein ligase (circ-ITCH) regulates sepsis-induced AKI.Methods A sepsis-induced AKI mouse mode...

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Bibliographic Details
Main Authors: Weidi Ye, Qi Miao, Guangxin Xu, Kai Jin, Xue Li, Weidong Wu, Lina Yu, Min Yan
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
Subjects:
circ-ITCH
microRNA-214-3p
sepsis-induced acute kidney injury
mitochondrial dysfunction
ABCA1
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2023.2261552

Internet

https://www.tandfonline.com/doi/10.1080/0886022X.2023.2261552

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