Add-On Cyclic Angiotensin-(1-7) with Cyclophosphamide Arrests Progressive Kidney Disease in Rats with ANCA Associated Glomerulonephritis

Add-On Cyclic Angiotensin-(1-7) with Cyclophosphamide Arrests Progressive Kidney Disease in Rats with ANCA Associated Glomerulonephritis

Rapidly progressive crescentic glomerulonephritis associated with anti-neutrophil cytoplasmic antibodies (ANCA-GN) is a major cause of renal failure. Current immunosuppressive therapies are associated with severe side effects, intensifying the need for new therapeutic strategies. The activation of M...

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Bibliographic Details
Main Authors: Domenico Cerullo, Daniela Rottoli, Daniela Corna, Mauro Abbate, Ariela Benigni, Giuseppe Remuzzi, Carlamaria Zoja
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
crescentic glomerulonephritis
myeloperoxidase
anti-neutrophil cytoplasmic antibodies
cyclophosphamide
angiotensin-(1-7)
glomerular crescents
Online Access:https://www.mdpi.com/2073-4409/11/15/2434

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https://www.mdpi.com/2073-4409/11/15/2434

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