DCR2, a Cellular Senescent Molecule, Is a Novel Marker for Assessing Tubulointerstitial Fibrosis in Patients with Immunoglobulin A Nephropathy

Background/Aims: Stress-induced cell senescence, which contributes to cell cycle arrest and is independent of age, plays an important role in chronic kidney disease (CKD) progression. DcR2, as a senescent marker, exclusively expressed in senescent tubular epithelia. The objective of this study was t...

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Bibliographic Details
Main Authors: Jia Chen, Wei Hu, Fei Xiao, Lirong Lin, Kehong Chen, Liming Wang, Xiaoyue Wang, Yani He
Format: Article
Language:English
Published: Karger Publishers 2019-09-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:https://www.karger.com/Article/FullText/502233