Sumoylation of Hes6 Regulates Protein Degradation and Hes1-Mediated Transcription
BackgroundHes6 is a transcriptional regulator that induces transcriptional activation by binding to transcription repressor Hes1 and suppressing its activity. Hes6 is controlled by the ubiquitin-proteosome-mediated degradation system. Here we investigated the sumoylation of Hes6 and its functional r...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Korean Endocrine Society
2015-09-01
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Series: | Endocrinology and Metabolism |
Subjects: | |
Online Access: | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-381.pdf |