Rickettsial pathogen inhibits tick cell death through tryptophan metabolite mediated activation of p38 MAP kinase
Summary: Anaplasma phagocytophilum modulates various cell signaling pathways in mammalian cells for its survival. In this study, we report that A. phagocytophilum modulates tick tryptophan pathway to activate arthropod p38 MAP kinase for the survival of both this bacterium and its vector host. Incre...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422202003X |