Rickettsial pathogen inhibits tick cell death through tryptophan metabolite mediated activation of p38 MAP kinase

Summary: Anaplasma phagocytophilum modulates various cell signaling pathways in mammalian cells for its survival. In this study, we report that A. phagocytophilum modulates tick tryptophan pathway to activate arthropod p38 MAP kinase for the survival of both this bacterium and its vector host. Incre...

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Bibliographic Details
Main Authors: Prachi Namjoshi, Mustapha Dahmani, Hameeda Sultana, Girish Neelakanta
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422202003X