ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism

ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism

Hepatic lipid droplet (LD) catabolism is thought to occur via cytosolic lipases such as adipose triglyceride lipase (ATGL) or through autophagy of LDs, a process known as lipophagy. We tested the potential interplay between these metabolic processes and its effects on hepatic lipid metabolism. We sh...

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Bibliographic Details
Main Authors: Aishwarya Sathyanarayan, Mara T. Mashek, Douglas G. Mashek
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Cell Reports
Subjects:
ATGL
autophagy
fatty acid oxidation
liver metabolism
lipid droplets
lipolysis
lipophagy
SIRT1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717303583

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717303583

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