DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation

DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation

Abstract Background Knowledge about regulating transcription factors (TFs) for osteoblastogenesis from mesenchymal stem cells (MSCs) is limited. Therefore, we investigated the relationship between genomic regions subject to DNA-methylation changes during osteoblastogenesis and the TFs known to direc...

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Bibliographic Details
Main Authors: Rodolfo Gómez, Matt J. Barter, Ana Alonso-Pérez, Andrew J. Skelton, Carole Proctor, Gabriel Herrero-Beaumont, David A. Young
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Biological Research
Subjects:
Osteoblastogenesis
Stem cell differentiation
Methylation
Bone adiposity
Online Access:https://doi.org/10.1186/s40659-023-00417-6

Internet

https://doi.org/10.1186/s40659-023-00417-6

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