Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

AIDS (acquired immunodeficiency syndrome) is a potentially life-threatening infectious disease caused by human immunodeficiency virus (HIV). To date, thousands of people have lost their lives annually due to HIV infection, and it continues to be a big public health issue globally. Since the discover...

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Bibliographic Details
Main Authors: Murugesan Vanangamudi, Senthilkumar Palaniappan, Muthu Kumaradoss Kathiravan, Vigneshwaran Namasivayam
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Viruses
Subjects:
HIV/AIDS
NNRTIs
structure- and fragment-based drug design
bioisosteric replacement
prodrug
scaffold hopping
Online Access:https://www.mdpi.com/1999-4915/15/10/1992

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https://www.mdpi.com/1999-4915/15/10/1992

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