Endothelial Immune Activation by Medin: Potential Role in Cerebrovascular Disease and Reversal by Monosialoganglioside‐Containing Nanoliposomes

Endothelial Immune Activation by Medin: Potential Role in Cerebrovascular Disease and Reversal by Monosialoganglioside‐Containing Nanoliposomes

Background The function of medin, one of the most common human amyloid proteins that accumulates in the vasculature with aging, remains unknown. We aim to probe medin's role in cerebrovascular disease by comparing cerebral arterial medin content between cognitively normal and vascular dementia...

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Bibliographic Details
Main Authors: Nina Karamanova, Seth Truran, Geidy E. Serrano, Thomas G. Beach, Jillian Madine, Volkmar Weissig, Hannah A. Davies, Jaimeson Veldhuizen, Mehdi Nikkhah, Michael Hansen, Weiyang Zhang, Karen D'Souza, Daniel A. Franco, Raymond Q. Migrino
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aging
amyloid
cerebrovascular disease
inflammation
vascular dementia
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.014810

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.014810

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