Blocking of connexin-mediated communication promotes neuroprotection during acute degeneration induced by mechanical trauma.

Blocking of connexin-mediated communication promotes neuroprotection during acute degeneration induced by mechanical trauma.

Accruing evidence indicates that connexin (Cx) channels in the gap junctions (GJ) are involved in neurodegeneration after injury. However, studies using KO animal models endowed apparently contradictory results in relation to the role of coupling in neuroprotection. We analyzed the role of Cx-mediat...

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Bibliographic Details
Main Authors: Vera Paschon, Guilherme Shigueto Vilar Higa, Rodrigo Ribeiro Resende, Luiz Roberto G Britto, Alexandre Hiroaki Kihara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3447938?pdf=render

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http://europepmc.org/articles/PMC3447938?pdf=render

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