Characteristics and impact of infiltration of B-cells from systemic sclerosis patients in a 3D healthy skin model

Characteristics and impact of infiltration of B-cells from systemic sclerosis patients in a 3D healthy skin model

IntroductionIn systemic sclerosis (SSc), B-cells are activated and present in the skin and lung of patients where they can interact with fibroblasts. The precise impact and mechanisms of the interaction of B-cells and fibroblasts at the tissular level are poorly studied.ObjectiveWe investigated the...

Full description

Bibliographic Details
Main Authors: Mathilde Le Maître, Thomas Guerrier, Aurore Collet, Mehdi Derhourhi, Jean-Pascal Meneboo, Bénédicte Toussaint, Amélie Bonnefond, Céline Villenet, Shéhérazade Sebda, Antonino Bongiovanni, Meryem Tardivel, Myriam Simon, Manel Jendoubi, Blanche Daunou, Alexis Largy, Martin Figeac, Sylvain Dubucquoi, David Launay
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Immunology
Subjects:
B-cell
systemic sclerosis
skin
3D coculture
fibrosis
fibroblast
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1373464/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1373464/full

Similar Items