Cytokine Adsorption During Ex Vivo Blood Perfusion Improves Contractility of Donation After Circulatory Death Hearts

Cytokine Adsorption During Ex Vivo Blood Perfusion Improves Contractility of Donation After Circulatory Death Hearts

Background Donation after circulatory death (DCD) hearts have to withstand ischemia/reperfusion injury that is partially driven by proinflammatory cytokines and decreases ventricular contractility. We hypothesize that cytokine adsorption during normothermic ex vivo blood perfusion of DCD hearts redu...

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Bibliographic Details
Main Authors: Lars Saemann, Sabine Pohl, Kristin Wächter, Adrian‐Iustin Georgevici, Conny Köhler, Jennifer Jünger, Fabio Hoorn, Nitin Gharpure, Anne Großkopf, Sevil Korkmaz‐Icöz, Folker Wenzel, Matthias Karck, Andreas Simm, Gábor Szabó
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cytokine adsorption
cytokines
CytoSorb
donation after circulatory death
heart transplantation
machine perfusion
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.036872

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https://www.ahajournals.org/doi/10.1161/JAHA.124.036872

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