Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments

Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with remodelling of gap junctions and also, although less well-defined, down-regulation of the fast sodium current. The gap junction remodelling and down-regulation of sodium current have been proposed as contributors to...

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Bibliographic Details
Main Author: Ronald eWilders
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00168/full