Infrapatellar fat pad adipose tissue-derived macrophages display a predominant CD11c+CD206+ phenotype and express genotypes attributable to key features of OA pathogenesis

Infrapatellar fat pad adipose tissue-derived macrophages display a predominant CD11c+CD206+ phenotype and express genotypes attributable to key features of OA pathogenesis

ObjectivesIn knee osteoarthritis (OA), macrophages are the most predominant immune cells that infiltrate synovial tissues and infrapatellar fat pads (IPFPs). Both M1 and M2 macrophages have been described, but their role in OA has not been fully investigated. Therefore, we investigated macrophage su...

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Bibliographic Details
Main Authors: Patchanika Hengtrakool, Nitigorn Leearamwat, Panjana Sengprasert, Jutamas Wongphoom, Thiamjit Chaichana, Mana Taweevisit, Srihatach Ngarmukos, Aree Tanavalee, Tanapat Palaga, Rangsima Reantragoon
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
osteoarthritis
macrophage
macrophage polarization
synovial tissue
infrapatellar fat pad
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1326953/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1326953/full

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