Essential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1.

Essential and Checkpoint Functions of Budding Yeast ATM and ATR during Meiotic Prophase Are Facilitated by Differential Phosphorylation of a Meiotic Adaptor Protein, Hop1.

A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases. During meiosis, Tel1 and Mec1, the budding yeast ATM and ATR, respectively, rely on a meiotic adaptor protein Hop1, a 53BP1/Rad9 functi...

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Bibliografske podrobnosti
Main Authors: Ana Penedos, Anthony L Johnson, Emily Strong, Alastair S Goldman, Jesús A Carballo, Rita S Cha
Format: Article
Jezik:English
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4520594?pdf=render

Internet

http://europepmc.org/articles/PMC4520594?pdf=render

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