Multicomponent complex formation between pyrimethamine, cyclodextrins and water-soluble polymers

The combined effect of hydroxypropyl-β-cyclodextrin (HPβCD) and polyvinylpyrrolidone (PVP) or sodium carboxymethylcellulose (CMC) on the solubility of pyrimethamine (PYR) was studied. Equimolar PYR-HPβCD solid systems, in the presence or the absence of 0.25% (w/v) PVP or 0...

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Bibliographic Details
Main Authors: Leticia Norma Carpentieri Rodrigues, Michelle Georges Issa, Ana Carolina Cavassin Asbahr, Marco Aurélio Carvalho Silva, Humberto Gomes Ferraz
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2011-10-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000500014