The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

Abstract Background Reactive oxygen species (ROS) regulate the migration and invasion of fibroblast-like synoviocytes (FLS), which are key effector cells in rheumatoid arthritis (RA) pathogenesis. Nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) induces ROS generation and, consequently,...

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Bibliographic Details
Main Authors: Ha-Reum Lee, Su-Jin Yoo, Jinhyun Kim, In Seol Yoo, Chan Keol Park, Seong Wook Kang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Osteoarthritis
Fibroblast-like synoviocytes
Reactive oxygen species
NADPH
NOX4
Online Access:http://link.springer.com/article/10.1186/s13075-020-02204-0

Internet

http://link.springer.com/article/10.1186/s13075-020-02204-0

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