Nonmechanical Roles of Dystrophin and Associated Proteins in Exercise, Neuromuscular Junctions, and Brains

Nonmechanical Roles of Dystrophin and Associated Proteins in Exercise, Neuromuscular Junctions, and Brains

Dystrophin-glycoprotein complex (DGC) is an important structural unit in skeletal muscle that connects the cytoskeleton (f-actin) of a muscle fiber to the extracellular matrix (ECM). Several muscular dystrophies, such as Duchenne muscular dystrophy, Becker muscular dystrophy, congenital muscular dys...

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Bibliographic Details
Main Authors: Bailey Nichols, Shin'ichi Takeda, Toshifumi Yokota
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Brain Sciences
Subjects:
dystrophin
dystrophin-glycoprotein complex (DGC)
syntrophin
exercise
brain
tadalafil (Cialis®)
sildenafil citrate (Viagra®)
muscular dystrophy
neuronal nitric oxide synthase (nNOS)
two-hit hypothesis (two-hit theory)
Online Access:http://www.mdpi.com/2076-3425/5/3/275

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http://www.mdpi.com/2076-3425/5/3/275

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