Enzyme Activity of Natural Products on Cytochrome P450

Enzyme Activity of Natural Products on Cytochrome P450

Drug-metabolizing enzymes, particularly the cytochrome P450 (CYP450) monooxygenases, play a pivotal role in pharmacokinetics. CYP450 enzymes can be affected by various xenobiotic substrates, which will eventually be responsible for most metabolism-based herb–herb or herb–drug interactions, usually i...

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Bibliographic Details
Main Authors: Hua-Li Zuo, Hsi-Yuan Huang, Yang-Chi-Dung Lin, Xiao-Xuan Cai, Xiang-Jun Kong, Dai-Lin Luo, Yu-Heng Zhou, Hsien-Da Huang
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
natural product
herbal ingredient
cytochrome P450
herb–herb interaction
herb–drug interaction
combinatorial synergism
Online Access:https://www.mdpi.com/1420-3049/27/2/515

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https://www.mdpi.com/1420-3049/27/2/515

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