Pathogenesis of thoracic ossification of the ligamentum flavum

Thoracic ossification of the ligamentum flavum (TOLF) is characterized by ectopic ossification of the ligamentum flavum in the thoracic spine and is considered the main cause of thoracic spinal stenosis and spinal cord disease. Osteoblast specific transcription factor Osterix (Osx) is required for b...

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Bibliographic Details
Main Authors: Chi Zhang, Yanan Chang, Li Shu, Zhongqiang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1496297/full