A Golgi fragmentation pathway in neurodegeneration

A Golgi fragmentation pathway in neurodegeneration

The Golgi apparatus processes intracellular proteins, but undergoes disassembly and fragmentation during apoptosis in several neurodegenerative disorders such as amyotrophic lateral sclerosis and Alzheimer’s disease. It is well known that other cytoplasmic organelles play important roles in cell dea...

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Bibliographic Details
Main Authors: Saya Nakagomi, Mark J. Barsoum, Ella Bossy-Wetzel, Christine Sütterlin, Vivek Malhotra, Stuart A. Lipton
Format: Article
Language:English
Published: Elsevier 2008-02-01
Series:Neurobiology of Disease
Subjects:
Golgi fragmentation
ER stress
Apoptosis
Mitochondria
Alzheimer’s disease
Amyotrophic lateral sclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107002008

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http://www.sciencedirect.com/science/article/pii/S0969996107002008

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