ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures

Summary: The structure-specific endonuclease ERCC1/XPF plays an important role in nucleotide excision repair and interstrand cross-link repair. In this study, we identified new functions of ERCC1/XPF in DNA double-strand break (DSB) repair. We found that the conserved function of ERCC1/XPF to remove...

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Bibliographic Details
Main Authors: Shibo Li, Hongyan Lu, Zi Wang, Qing Hu, Hongjun Wang, Rong Xiang, Takuya Chiba, Xiaohua Wu
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219301543