Long-term adult human brain slice cultures as a model system to study human CNS circuitry and disease

Long-term adult human brain slice cultures as a model system to study human CNS circuitry and disease

Most of our knowledge on human CNS circuitry and related disorders originates from model organisms. How well such data translate to the human CNS remains largely to be determined. Human brain slice cultures derived from neurosurgical resections may offer novel avenues to approach this translational...

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Bibliographic Details
Main Authors: Niklas Schwarz, Betül Uysal, Marc Welzer, Jacqueline C Bahr, Nikolas Layer, Heidi Löffler, Kornelijus Stanaitis, Harshad PA, Yvonne G Weber, Ulrike BS Hedrich, Jürgen B Honegger, Angelos Skodras, Albert J Becker, Thomas V Wuttke, Henner Koch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
adult human neurons
morphology
human brain slice cultures
spines
Online Access:https://elifesciences.org/articles/48417

Internet

https://elifesciences.org/articles/48417

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