Inducing Angiogenesis in the Nucleus Pulposus

Inducing Angiogenesis in the Nucleus Pulposus

Bone morphogenetic protein (BMP) gene delivery to Lewis rat lumbar intervertebral discs (IVDs) drives bone formation anterior and external to the IVD, suggesting the IVD is inhospitable to osteogenesis. This study was designed to determine if IVD destruction with a proteoglycanase, and/or generating...

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Bibliographic Details
Main Authors: Sheela R. Damle, Agata K. Krzyzanowska, Maximilian K. Korsun, Kyle W. Morse, Susannah Gilbert, Han Jo Kim, Oheneba Boachie-Adjei, Bernard A. Rawlins, Marjolein C. H. van der Meulen, Matthew B. Greenblatt, Chisa Hidaka, Matthew E. Cunningham
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
intervertebral disc
angiogenesis
osteogenesis
fusion
gene delivery
proteoglycanase nucleus pulposus
Online Access:https://www.mdpi.com/2073-4409/12/20/2488

Internet

https://www.mdpi.com/2073-4409/12/20/2488

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