Multiplex CRISPRi System Enables the Study of Stage-Specific Biofilm Genetic Requirements in <named-content content-type="genus-species">Enterococcus faecalis</named-content>

Multiplex CRISPRi System Enables the Study of Stage-Specific Biofilm Genetic Requirements in <named-content content-type="genus-species">Enterococcus faecalis</named-content>

ABSTRACT Enterococcus faecalis is an opportunistic pathogen, which can cause multidrug-resistant life-threatening infections. Gaining a complete understanding of enterococcal pathogenesis is a crucial step in identifying a strategy to effectively treat enterococcal infections. However, bacterial pat...

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Bibliographic Details
Main Authors: Irina Afonina, June Ong, Jerome Chua, Timothy Lu, Kimberly A. Kline
Format: Article
Language:English
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
Enterococcus faecalis
CRISPR interference
biofilms
gene essentiality
Ebp pili
Online Access:https://journals.asm.org/doi/10.1128/mBio.01101-20

Internet

https://journals.asm.org/doi/10.1128/mBio.01101-20

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