Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2

Summary: Current COVID-19 vaccines have been associated with a decline in infection rates, prevention of severe disease, and a decrease in mortality rates. However, SARS-CoV-2 variants are continuously evolving, and development of new accessible COVID-19 vaccines is essential to mitigate the pandemi...

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Main Authors: Antonio Barreiro, Antoni Prenafeta, Gregori Bech-Sabat, Mercè Roca, Eva Perozo Mur, Ricard March, Luis González-González, Laia Madrenas, Júlia Corominas, Alex Fernández, Alexandra Moros, Manuel Cañete, Mercè Molas, Thais Pentinat-Pelegrin, Clara Panosa, Alberto Moreno, Ester Puigvert Molas, Eva Pol Vilarrassa, Jordi Palmada, Carme Garriga, Teresa Prat Cabañas, Javier Iglesias-Fernández, Júlia Vergara-Alert, Cristina Lorca-Oró, Núria Roca, Leira Fernández-Bastit, Jordi Rodon, Mònica Pérez, Joaquim Segalés, Edwards Pradenas, Silvia Marfil, Benjamin Trinité, Raquel Ortiz, Bonaventura Clotet, Julià Blanco, Jorge Díaz Pedroza, Rosa Ampudia Carrasco, Yaiza Rosales Salgado, Jordina Loubat-Casanovas, Sara Capdevila Larripa, Julia Garcia Prado, Jordi Barretina, Marta Sisteré-Oró, Paula Cebollada Rica, Andreas Meyerhans, Laura Ferrer
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223002031