Genomic Characterization of KPC-31 and OXA-181 <i>Klebsiella pneumoniae</i> Resistant to New Generation of β-Lactam/β-Lactamase Inhibitor Combinations

Genomic Characterization of KPC-31 and OXA-181 <i>Klebsiella pneumoniae</i> Resistant to New Generation of β-Lactam/β-Lactamase Inhibitor Combinations

Background: Carbapenem resistant <i>Klebsiella pneumoniae</i> (cr-Kp) causes serious infections associated with a high mortality rate. The clinical efficacy of ceftazidime/avibactam (CZA), meropenem/vaborbactam (M/V), and imipenem/relebactam (I/R) against cr-Kp is challenged by the emerg...

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Bibliographic Details
Main Authors: Narcisa Muresu, Arcadia Del Rio, Valeria Fox, Rossana Scutari, Claudia Alteri, Bianca Maria Are, Pierpaolo Terragni, Illari Sechi, Giovanni Sotgiu, Andrea Piana
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Antibiotics
Subjects:
carbapenem resistant Enterobacteriaceae
antimicrobial resistance
whole genome sequencing
KPC variants
porin mutations
<i>Klebsiella pneumoniae</i>
Online Access:https://www.mdpi.com/2079-6382/12/1/10

Internet

https://www.mdpi.com/2079-6382/12/1/10

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