Potential Application of Recombinant Snake Prothrombin Activator Ecarin in Blood Diagnostics

Potential Application of Recombinant Snake Prothrombin Activator Ecarin in Blood Diagnostics

We describe here the purification and cloning of a codon-optimized form of the snake prothrombin activator ecarin from the saw scaled viper (<i>Echis carinatus</i>) expressed in mammalian cells. Expression of recombinant ecarin (rEcarin) was carried out in human embryonic kidney cells (H...

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Bibliographic Details
Main Authors: Kong-Nan Zhao, Paul Masci, Goce Dimeski, Lambro Johnson, Michael Grant, John de Jersey, Martin F. Lavin
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomolecules
Subjects:
recombinant ecarin
blood clotting
clotting of anticoagulated blood
high quality serum
Online Access:https://www.mdpi.com/2218-273X/12/11/1704

Internet

https://www.mdpi.com/2218-273X/12/11/1704

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