Strong upregulation of inflammatory genes accompanies photoreceptor demise in canine models of retinal degeneration.

We have analyzed the complex pattern of the inflammatory response in early-onset canine models of human retinitis pigmentosa, rcd1, xlpra2 and erd, as well as late-onset xlpra1, in comparative manner. The time course of immune response genes and proteins expression was examined along the timeline of...

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Bibliographic Details
Main Authors: Tatyana Appelbaum, Evelyn Santana, Gustavo D Aguirre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5423635?pdf=render