The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression

The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression

Ebola virus (EBOV) causes severe outbreaks of viral hemorrhagic fever in humans. While virus-host interactions are promising targets for antivirals, there is only limited knowledge regarding the interactions of EBOV with cellular host factors. Recently, we performed a genome-wide siRNA screen that i...

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Bibliographic Details
Main Authors: Lisa Wendt, Janine Brandt, Bianca S. Bodmer, Sven Reiche, Marie Luisa Schmidt, Shelby Traeger, Thomas Hoenen
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
ebola virus
filovirus
inclusion bodies
nxf1
liquid organelles
mrna export
Online Access:https://www.mdpi.com/2073-4409/9/1/187

Internet

https://www.mdpi.com/2073-4409/9/1/187

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