Understanding In Vivo Fate of Nucleic Acid and Gene Medicines for the Rational Design of Drugs

Understanding In Vivo Fate of Nucleic Acid and Gene Medicines for the Rational Design of Drugs

Nucleic acid and genetic medicines are increasingly being developed, owing to their potential to treat a variety of intractable diseases. A comprehensive understanding of the in vivo fate of these agents is vital for the rational design, discovery, and fast and straightforward development of the dru...

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Bibliographic Details
Main Authors: Shintaro Fumoto, Tsuyoshi Yamamoto, Kazuya Okami, Yuina Maemura, Chisato Terada, Asako Yamayoshi, Koyo Nishida
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
liposome
lipid nanoparticle
plasmid DNA
oligonucleotide
transfection
mechanism
Online Access:https://www.mdpi.com/1999-4923/13/2/159

Internet

https://www.mdpi.com/1999-4923/13/2/159

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