SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways

SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways

Summary: Hemogenic endothelium (HE) is the main source of blood cells in the embryo. To improve blood manufacturing from human pluripotent stem cells (hPSCs), it is essential to define the molecular determinants that enhance HE specification and promote development of the desired blood lineage from...

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Bibliographic Details
Main Authors: Ho Sun Jung, Kran Suknuntha, Yun Hee Kim, Peng Liu, Samuel T. Dettle, Divine Mensah Sedzro, Portia R. Smith, James A. Thomson, Irene M. Ong, Igor I. Slukvin
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Components of the immune system
Stem cells research
Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223006983

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http://www.sciencedirect.com/science/article/pii/S2589004223006983

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