1H Nuclear Magnetic Resonance (NMR) Metabolomic Study of Chronic Organophosphate Exposure in Rats

1H NMR spectroscopy and chemometric analysis were used to characterize rat urine obtained after chronic exposure to either tributyl phosphate (TBP) or triphenyl phosphate (TPP). In this study, the daily dose exposure was 1.5 mg/kg body weight for TBP, or 2.0 mg/kg body weight for TPP, administered o...

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Bibliographic Details
Main Authors: Todd M. Alam, Muniasamy Neerathilingam, M. Kathleen Alam, David E. Volk, G. A. Shakeel Ansari, Swapna Sarkar, Bruce A. Luxon
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Metabolites
Subjects:
Online Access:http://www.mdpi.com/2218-1989/2/3/479