1H Nuclear Magnetic Resonance (NMR) Metabolomic Study of Chronic Organophosphate Exposure in Rats
1H NMR spectroscopy and chemometric analysis were used to characterize rat urine obtained after chronic exposure to either tributyl phosphate (TBP) or triphenyl phosphate (TPP). In this study, the daily dose exposure was 1.5 mg/kg body weight for TBP, or 2.0 mg/kg body weight for TPP, administered o...
Main Authors: | Todd M. Alam, Muniasamy Neerathilingam, M. Kathleen Alam, David E. Volk, G. A. Shakeel Ansari, Swapna Sarkar, Bruce A. Luxon |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-07-01
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Series: | Metabolites |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-1989/2/3/479 |
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