Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice

Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice

Abstract Background E. coli O83 (Colinfant Newborn) is a Gram-negative (G-) probiotic bacterium used in the clinic. When administered orally, it reduces allergic sensitisation but not allergic asthma. Intranasal administration offers a non-invasive and convenient delivery method. This route bypasses...

Full description

Bibliographic Details
Main Authors: Anna Marlene Schmid, Agnieszka Razim, Magdalena Wysmołek, Daniela Kerekes, Melissa Haunstetter, Paul Kohl, Georgii Brazhnikov, Nora Geissler, Michael Thaler, Eliška Krčmářová, Martin Šindelář, Tamara Weinmayer, Jiří Hrdý, Katy Schmidt, Peter Nejsum, Bradley Whitehead, Johan Palmfeldt, Stefan Schild, Aleksandra Inić-Kanada, Ursula Wiedermann, Irma Schabussova
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
Allergic airway inflammation
Extracellular vesicles
Outer membrane vesicles
Microbiota and innate immunity
Nasal route of administration
Online Access:https://doi.org/10.1186/s12964-023-01329-4

Internet

https://doi.org/10.1186/s12964-023-01329-4

Similar Items