Artificial Small Molecules as Cofactors and Biomacromolecular Building Blocks in Synthetic Biology: Design, Synthesis, Applications, and Challenges

Artificial Small Molecules as Cofactors and Biomacromolecular Building Blocks in Synthetic Biology: Design, Synthesis, Applications, and Challenges

Enzymes are essential catalysts for various chemical reactions in biological systems and often rely on metal ions or cofactors to stabilize their structure or perform functions. Improving enzyme performance has always been an important direction of protein engineering. In recent years, various artif...

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Bibliographic Details
Main Authors: Fenghua Liu, Lingling He, Sheng Dong, Jinsong Xuan, Qiu Cui, Yingang Feng
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
artificial small molecules
biological metal cluster mimics
coenzyme analogs
designer cofactors
non-natural nucleotides
non-natural amino acids
Online Access:https://www.mdpi.com/1420-3049/28/15/5850

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https://www.mdpi.com/1420-3049/28/15/5850

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