Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs

Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs

We analyzed transcriptomic data from otic sensory cells differentiated from human induced pluripotent stem cells (hiPSCs) by a previously described method to gain new insights into the early human otic neurosensory lineage. We identified genes and biological networks not previously described to occu...

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Bibliographic Details
Main Authors: Lejo Johnson Chacko, Hanae Lahlou, Claudia Steinacher, Said Assou, Yassine Messat, József Dudás, Albert Edge, Berta Crespo, Moira Crosier, Consolato Sergi, Anneliese Schrott-Fischer, Azel Zine
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
human induced pluripotent stem cells
otic sensory progenitors
gene expression analysis
extracellular matrix
integrins
human fetal inner ear
Online Access:https://www.mdpi.com/1422-0067/22/19/10849

Internet

https://www.mdpi.com/1422-0067/22/19/10849

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