Myeloid subsets impede the efficacy of anti-PD1 therapy in patients with advanced gastric cancer (WJOG10417GTR study)

Background Gastric cancer (GC) is one of the most common and deadly malignant diseases worldwide. Despite revolutionary advances, the therapeutic efficacy of anti-PD1/PDL1 monoclonal antibodies in advanced GC is still low due to the emergence of innate and acquired resistance to treatment. Myeloid c...

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Bibliographic Details
Main Authors: Naoki Takahashi, Hirokazu Shoji, Kengo Nagashima, Hiroshi Imazeki, Narikazu Boku, Takeshi Kawakami, Kei Muro, Takeru Wakatsuki, Chie Kudo-Saito, Yukiya Narita, Kai Tsugaru, Yusuke Amanuma, Naohiro Okano, Yoshiyuki Yamamoto, Rika Kizawa, Kazunori Aoki
Format: Article
Language:English
Published: BMJ Publishing Group 2024-11-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/11/e010174.full