Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis

Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis

Introduction: The perturbations of gut microbiota could interact with excessively activated immune responses and play key roles in the etiopathogenesis of ulcerative colitis (UC). Desulfovibrio, the most predominant sulfate reducing bacteria (SRB) resided in the human gut, was observed to overgrow i...

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Bibliographic Details
Main Authors: Yaping An, Zihan Zhai, Xin Wang, Yiyun Ding, Linlin He, Lingfeng Li, Qi Mo, Chenlu Mu, Runxiang Xie, Tianyu Liu, Weilong Zhong, Bangmao Wang, Hailong Cao
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Journal of Advanced Research
Subjects:
Ulcerative colitis
Desulfovibrio vulgaris
NAIP/NLRC4 inflammasome
Pyroptosis
Eugeniin
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123223002242

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http://www.sciencedirect.com/science/article/pii/S2090123223002242

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