High Mobility Group Box 1: Biological Functions and Relevance in Oxidative Stress Related Chronic Diseases

High Mobility Group Box 1: Biological Functions and Relevance in Oxidative Stress Related Chronic Diseases

In the early 1970s, a group of non-histone nuclear proteins with high electrophoretic mobility was discovered and named high-mobility group (HMG) proteins. High-mobility group box 1 (HMGB1) is the most studied HMG protein that detects and coordinates cellular stress response. The biological function...

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Bibliographic Details
Main Authors: Simona Taverna, Alessandro Tonacci, Maria Ferraro, Giuseppe Cammarata, Giuseppina Cuttitta, Salvatore Bucchieri, Elisabetta Pace, Sebastiano Gangemi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
high-mobility group box 1
damage-associated molecular pattern molecules
inflammation
oxidative stress related chronic diseases
cancer
diabetes
Online Access:https://www.mdpi.com/2073-4409/11/5/849

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https://www.mdpi.com/2073-4409/11/5/849

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