Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice
Methionine restriction (MR) dramatically extends the healthspan of several organisms. Methionine-restricted rodents have less age-related pathology and increased longevity as compared with controls, and recent studies suggest that humans might benefit similarly. Mechanistically, it is likely that th...
Main Authors: | Jason D Plummer, Spike DL Postnikoff, Jessica K Tyler, Jay E Johnson |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/62483 |
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